New Drug Targets Fat Cells
Have you tried everything to lose belly fat?
You know, the ab workouts that leave you incapacitated for days, the diets that just make you want to eat the whole fridge, the gadgets that gather dust after a few tries (because they do not work) and the depressing moments in front of the mirror when you pull your jeans on?
Well, a team of researchers, including Dr. Renata Pasqualini, of MD Anderson‘s David H. Koch Center for Applied Research for Genitourinary Cancers, and Wadih Arap, a professor at the Koch Center has developed a drug called ‘Adipotide’ to combat the adipose fat around the waist.
How It Works
The process known as angiogenesis inhibition was first developed to fight cancer in the brain, lungs, colon and kidneys.
Adipotide is made up of a homing agent that hangs on to a protein on the surface of fat-supporting blood vessels. Fat cells are then killed off by restricting or inhibiting the blood supply to them
Trials of injections on fat mice and over weight Rhesus monkeys showed a 30% and 27% reduction in fat respectively. The animals were able to eat less, lose belly fat and showed changes in their metabolism.
The experiment with injections lasted four weeks and four weeks of follow up with no treatment. Interestingly, fat loss was at its highest three weeks into the follow up period. No changes were made to exercise or to diet and the monkeys continued to lose weight and become leaner.
By keeping obesity at bay, chances of getting type II diabetes, heart diseases and other obesity related illnesses are lessen. Let’s hope that Adipotide will be available for humans soon to lose belly fat.